The 300C SRT8's 317 kW, 6.1-litre HEMI has the highest output for its size of any naturally aspirated V8 engine ever offered by the Chrysler Group. Its 52.05 kW-per-litre rating exceeds even that of the legendary 1966 `Street HEMI.' Torque is rated at 569 Nm.

To further increase power, performance-oriented camshaft profiles were developed to allow more air in and out of the cylinders, as well as manage a higher engine speed. SRT engineers increased the HEMI's peak power output engine speed to 6,200 revolutions per minute (rpm) from 5,000 rpm. Intake and exhaust valve stems are hollow, and the exhaust valve stems are filled with sodium to help dissipate heat more efficiently.

Power for the SRT 6.1-litre HEMI is channelled through a five-speed automatic transmission with specially calibrated driver-selectable AutoStick®, which offers fully automatic or manual shifting selection. A heavy-duty four-flange prop shaft sends the torque from the transmission to an upgraded differential and axles.

The 300C SRT8 is conditioned for outstanding ride and handling across the dynamic range that customers are likely to experience. The 2006 Chrysler 300C SRT8 connects with the road via a new wheel and tyre assembly consisting of 20-inch forged alloy wheels shod with high-performance Goodyear F1 three-season tyres with asymmetrical tread.